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2016-2017学年第一学期航空航天系第八期学术讲座
发表时间:2016-10-24 阅读次数:525次

题目:Haemodynamics application in Cerebrovascular Disease Treatment; Endovascular, Surgical Treatment, Device R&D,and Treatment Optimization

主讲:Yi Qian Professor

主持:王盛章 副教授

时间:20161025日(周二)下午13:30

地点:光华楼东主楼2601

 

教授简介

Prof. Qian has 30 years continuous experience in fluid dynamics research, 20 years experiences in the area of translation medicine. He has worked in the field of circulatory assist and was instrumental in the development of the artificial heart devices. He primarily developed circulatory assist devices. The devices has been implanted over 500 patients around world. Dr. Qian has developed haemodynamic techniques for application to research in studies of haemodynamics and mechanisms of rupture of cerebral aneurysms. The haemodynamic system has been applied to over 2000 aneurysm patients, and has been introduced into daily clinical diagnosis application. He has developed novel methodologies for improvement vascular surgical methods. These have begun to be applied in pilot studies to assess the clinical applicability. Dr. Qian is also interesting in medical image analysis, cancer treatment, surgery navigation technology, nano-technology development and application, and neuron-network.

内容简介

Aneurysms are treated by excluding the aneurysm sacs from the jet flow of blood circulation through either the process of open surgical clipping or by endovascular coiling through the arteries. The rationale for treating unruptured aneurysms is to prevent future rupture resulting in catastrophic 1-month case fatality rates of 25 to 60%. Endovascular coiling has been shown to have a better outcome than surgical clipping in the treatment of ruptured aneurysms. Moreover there are some 108,000 cases per year, worldwide, treated through the use of coiling, of which 16,000 cases will need to be assisted with stents, and almost same number of cases which treated by surgical clipping. However, long term results are not yet available but current experience is promising. There were, however, concerns regarding the inconsistency of endovascular performance. The time frame for complete occlusion is unknown. Haemodynamic factors, such as blood jet flow intensity and aneurysm wall shear stress (WSS), are considered to play an important role in the development and rupture of intracranial aneurysms. Adverse haemodynamics has been implicated as one of the main factors behind delayed rupture and delayed occlusion of the aneurysm. Computational fluid dynamics (CFD) is a branch of fluid mechanics that uses numerical methods to solve and analyse problems that involve blood flows. Hence development of an accurate CFD model would enable accurate simulations for determination of the haemodynamic parameters that promote aneurysm occlusion or otherwise, a result that can then be applied in treatment planning and advancement of endovascular and virtual design for clipping surgery.

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